8 Best Mushroom Supplements To Boost Your Health (In 2023)

Thank you for reading this post, don't forget to subscribe!

Since ancient times, people have known that, in addition to being valued for
their distinctive flavors and culinary flexibility, mushrooms may provide
health benefits. So, it’s no surprise that those benefits have been harnessed
for modern-day consumers in the form of nutritional supplements.

Mushroom supplements provide a convenient way to strengthen your immunity,
boost your brain power, and enhance your overall well-being. In this article,
we review the eight best mushroom supplements on the current market, so you
can start unlocking all of the juicy benefits ASAP.

8 Best Mushroom Supplements

  1. Overall Best Mushroom Supplement – Longevity Botanicals Power Blend 15
  2. Best Mushroom Supplement For Brain Health – Transparent Lab Shroom Stack
  3. Best Mushroom Supplement For Boosting Mood – Longevity Botanicals Emperor Four Blend
  4. Best Cordyceps Mushroom Supplement – Real Mushrooms Cordyceps-M
  5. Best Mushroom Supplement For Anxiety – Longevity Botanicals Super Six Blend
  6. Best Reishi Mushroom Supplement – Life Extension Reishi Mushroom Extract Complex
  7. Best Turkey Tail Mushroom Supplement – Longevity Botanicals Turkey Tail
  8. Best Lion’s Mane Mushroom Supplement – Host Defense Lion’s Mane
best mushroom supplement for brain

With their
Power Blend 15 Mushroom Supplement, Longevity Botanicals offers a complete wellness solution. Each ingredient
in this carefully formulated blend of 15 mushroom species is hand-selected for
its distinct potential benefits and supported by scientific study.

The Power Blend 15 Mushroom Supplement offers a range of health benefits, from
immunological modulation and cognitive support to stress resistance and
cardiovascular wellness. Reishi, Lion’s Mane, Cordyceps, Chaga, and other
varied mushrooms are combined to provide a dynamic synergy of bioactive
substances. Each species is extracted using the superior hot water extraction

Longevity Botanicals’ philosophy is based on quality and purity. As such, you
can be assured that this premium supplement meets the highest standards thanks
to rigorous testing and open sourcing.

Power Blend 15 is offered as a 100-gram pouch, providing 60 servings. Simply
add a scoop to your coffee, tea, or other favorite beverage to supercharge it
with the power of the mushroom fungi.

Power Blend 15 is also available as a capsule in a 90-count bottle.

  • +A blend of 15 species of mushroom
  • +Hot water extraction method
  • +Rigorously tested for potency and purity
  • Does not mix overly well with beverages
best mushroom supplement blend

The appropriately named Power Blend 15 provides 1600mg of hot-water extracted mushrooms. Made from a blend of the most well-known and effective mushrooms, Power Blend 15 is a great way to…

best mushroom supplement for anxiety

Shroom Stack by Transparent Labsblends the three most well-recognized mushroom species for overall

  • Reishi- 500 mg

  • Lion’s Mane – 1 g

  • Cordyceps – 500 mg

These species are especially well known for their brain-boosting ability.
Lion’s Mane is the standout ingredient for improving cognitive performance and
supporting nerve health by stimulating brain cell development.

In addition to its cognitive benefits, Shroom Stack’s blend of three powerful
fungi will improve workout performance, boost immunity, and support cellular
health to slow the aging process. The company has built its reputation on
providing the transparency and open sourcing-that its name suggests, and this
product is yet another example of that high standard.

Transparent Labs Shroom Stack uses only organic mushrooms in capsule form, and
the recommended dosage is three capsules per day on an empty stomach.

  • +A blend of three power mushroom species
  • +Boosts brain power
  • +Organic mushrooms
  • +Well priced
  • Not many verified customer reviews on the official website
best mushroom supplement for inflammation

The mushrooms in TL Mushroom Stack are packed with bioactive constituents that promote overall health and longevity through diverse mechanisms across multiple body systems, especially the…

best mushroom supplement for adhd

Emperor Four Blendfrom Longevity Botanicals provides 400 mg each of the following
medicinal mushrooms species:

  • Lion’s Mane

  • Red Reishi

  • Cordyceps

  • Chaga

This is an excellent blend for those looking to boost their mood through
mushroom powders. To start, Lion’s Mane is abundant in compounds that promote
brain health and wellness, which can contribute to elevated mood and
well-being. Red Reishi is known for its adaptogenic properties and ability to
support sleep. Cordyceps can boost physical performance, encouraging an active
lifestyle that can improve a person’s mood. Finally, Chaga promotes mood
balance with its powerful antioxidant properties.

Organic Emperor Four Blend comes in powder form as a 100-gram pouch. That’s
enough for sixty servings. As with Power Blend 15, you can add a scoop of the
powder to your favorite hot or cold beverage.

Longevity Botanicals makes use of an advanced hot water extraction method to
extract the active ingredients from the mushrooms. The label of this and all
other Longevity mushroom products also stand out by displaying the percentage
of beta-d glucans – the main beneficial compounds – in the product. This
mushroom powder contains no fillers or grains and is also free of mycelium,
starch, fillers, or gluten.

  • +A blend of four mood-enhancing mushroom species
  • +Advanced hot water extraction method used
  • +The label displays the beta-d glucan percentage
  • It does not mix very well
best functional mushroom supplements

Longevity Botanical’s Emperor Four Blend is made from hot-water extracted Lion’s Mane, Red Reishi, Cordyceps, Chaga mushrooms, providing a potent and effective way to improve your…

best mushroom blend supplement

Real Mushrooms Cordyceps-M
contains only one type of mushroom, cordyceps. Known as the energy-boosting
and fatigue-fighting mushroom, the particular type of cordyceps mushroom used
here is cordyceps militarist – that’s what the ‘m’ stands for. The advantage
of this type is that, unlike cordyceps sinensis, it can be cultivated
organically without insects.

You get 1 gram of cordyceps militarist in every serving of Real Mushrooms
Cordyceps-M. It comes in capsule form, with the recommended daily dosage being
two capsules. Only organic mushrooms are used to maximize the benefits of the
extracted beta-glucans. The label states how much beta-glucans you get – 250

The only other ingredients are those that make up the capsule containing the
cordyceps powder. The capsule is made of hypromellose, which is
vegan-friendly. Unlike many competing products, Real Mushrooms Cordyceps-M has
no grains or starchy fillers.

Real Mushrooms excel at providing transparency and purity. A 2017 study
conducted byNaturemagazine found
that three-quarters of all mushroom products on the market were inauthentic,
with many containing fillers.Naturerated Real mushrooms as the best in terms of purity.

  • +Contains cordyceps militarist
  • +250 mg of beta-glucans
  • +Organic
  • It may cause sleep interruptions
best cordyceps mushroom supplement

Made using hand-picked Cordyceps Militaris mushroom extract, this mushroom supplement provides impressive benefits to support your overall well-being…

best time to take mushroom supplements

This is the third showing by Longevity Botanicals on our top eight mushroom
supplements list. That tells you a lot about the credibility and high
standards that this company sets and maintains. This particular product,
Super Six Blend, combines the following varieties of fungi:

  1. Organic Reishi

  2. Cordyceps (Militaris)

  3. Lion’s Mane

  4. Chaga

  5. Shiitake

  6. Turkey Tail

The research attested that the anxiety-alleviating benefits of these six
species make Longevity Botanicals Super Six the best mushroom supplement for
depression and anxiety.

This blend is guaranteed to have a minimum of 31% beta-glucans – the key
active ingredient that powers all the benefits of mushrooms. This product is a
100% Certified Organic Fruiting Body, giving you absolute confidence that it
contains no fillers or mycelium. Like all other Longevity Botanicals
mushrooms, the Super Six blend uses an advanced hot water extraction system to
optimize bioavailability.

The Super Six powder packed into capsules is micronized to ensure greater
bioavailability and a larger surface area. The capsules are vegan-friendly,
organic, gluten-free, and certified kosher. This product is also available as
a powder, which comes in a 100-gram sachet that provides 60 servings.

  • +Six mushroom species that have proven anxiety-relieving effects
  • +31% beta-glucans
  • +100% Certified Organic Fruiting Body
  • The powder form does not blend very well
best mushroom supplements for immune system

The Longevity Botanicals Super Six Blend consists of a hot-water extracted blend of Lion’s Mane, Red Reishi, Cordyceps, Chaga, Tremella and Turkey Tail. Using 100% fruiting bodies…

best mushroom supplements for brain

Reishi mushrooms have been used for centuries to improve immune function,
provide adaptogenic properties, enhance cardiovascular health, and deliver a
powerful antioxidant boost. The best reishi mushroom supplement is
Life Extension Reishi Mushroom Extract Complex, which provides a blend of the most potent types of Reishi mushrooms.

Life Extension uses an advanced extraction system to ensure that the product
you get contains the most pure, bioavailable mushroom ingredients possible.

You get 980 mg of Reishi mushroom extract (standardized to 13.5%
polysaccharides and 6% triterpenes, along with 150 mg of shell-broken Reishi

These ingredients are put into vegetarian capsule form, with the recommended
dosage at two capsules per day. This product is manufactured in the USA, with
a certificate of analysis available to attest to its potency and purity.

  • +A blend of three different types of reishi mushroom
  • +Advanced extraction system
  • +Certificate of Analysis available
  • It does not specify beta-glucans
best mushrooms supplement

Reishi mushroom compounds are powerful immune modulators. And this ultra-bioavailable Reishi formula uses an extract standardized for three active compounds…

best mushroom supplement for weight loss

Yet another Longevity Botanical supplement shows up on our best-of list, this
time representing the best
Turkey Tail mushroom supplementon the market.

Turkey Tail mushroom has been shown to strengthen the immune system. Its
ingredients like polysaccharopeptides and beta-glucans can activate the immune
cells such as macrophages and natural killer cells. Turkey Tail may also
improve gut health by encouraging the development of good gut bacteria. It
might also positively affect the respiratory system and help treat disorders,
including allergies and asthma.

Each three-capsule serving of Longevity Botanicals Turkey Tail contains 900 mg
of 100% fruiting body turkey tail, which is hot water extracted for optimum
bioavailability. The product is USDA-certified organic and guaranteed to
contain no less than 50% beta-glucans. That means you won’t find any starch,
fillers, or mycelium in it.

Each Longevity Botanicals Turkey Tail bottle provides 120 capsules, giving you
the equivalent of 40 servings.

  • +Pure turkey tail mushroom
  • +At least 50% beta-glucans
  • +USDA-Certified Organic
  • It may have a prominent odor, according to some reviewers
best mushrooms supplements

Longevity Botanicals Turkey Tail is made from 100% hot-water extracted fruiting body. Boasting >50% Beta-glucans, Longevity Botanicals provides one of the highest-quality products…

best mushroom supplements reddit

Host Defense Lion’s Mane
is the best Lion’s Mane mushroom supplement, providing you with one gram of
Lion’s Mane mushroom per serving. Lion’s Mane has some remarkable potential
advantages for cognitive health.

It is rich in substances that stimulate nerve growth factors (NGFs). These may
help with brain function, memory, and general cognitive health. Additionally,
this fungus’ anti-inflammatory and antioxidant qualities may protect against
cognitive deterioration.

Host Defense Lion’s Mane comes in capsule form, featuring 30, 60, and 120
capsule bottles. With the recommended serving being two capsules daily, a
30-capsule bottle will last 15 days. For $19.95 on the official website,
you’ll be spending $40 per month, which is comparatively expensive.

  • +1 gram of Lion’s Mane mushroom
  • +Rich in nerve growth factors (NGFs)
  • +Improves cognitive functioning
best way to take mushroom supplements

Harness the cognitive power of Lion’s Mane mushrooms. This formula delivers organic mushroom mycelium to help improve mental clarity, memory and your ability to focus. Grown in the USA, Host Defense…

Benefits Of Mushroom Supplements

Mushroom supplements have become popular as natural sources of several
nutrients and fungi compounds that support well-being. Let’s examine some of
the main benefits of adding mushroom supplements to your wellness routine.

1) Immune Health Support

Reishi, Shiitake, and Turkey Tail mushrooms are rich in bioactive extracts
that may improve immune system performance. These mushrooms have
polysaccharides and beta-glucans that may boost immune cells and
help the body fight off diseases and infections [1].

The polysaccharides and beta-glucans in varieties including Reishi, Shiitake,
and Turkey Tail are thought to boost immune cells like macrophages and natural
killer cells. These compounds work in concert with the immune system to
strengthen its defenses against pathogens, possibly helping keep diseases and
infections at bay. For instance, Reishi has been investigated for its
potential to promote immune cell function and immunomodulatory
effects [2]. Lentinan, a substance found in shiitake mushrooms, may improve
immunological response.

Polysaccharide-rich Turkey Tail mushrooms may aid in the control of the immune
system. Including these mushroom supplements in your regimen may provide a
natural means of boosting your immune health, especially when you are more
prone to infections.

2) Cognitive Health

Cognitive health benefits have been connected to lion’s mane and cordyceps
mushrooms. Lion’s Mane contains compounds that stimulate nerve growth factors
that may support cognitive processes like memory and learning. The ability of
cordyceps to improve oxygen uptake is also known to affect cognitive function.

Hericenones and erinacines, found in Lion’s Mane and thought to stimulate the
creation of nerve growth factors, are essential for the health of neurons and
proper brain function. According to research, taking Lion’s Mane
supplements may have neuroprotective properties and improve memory and
learning [3].

Cordyceps has been linked to improved oxygen utilization, which may assist
both energy metabolism and cognitive function.

3) Stress Adaptation

It’s thought that several mushroom supplements, including Reishi
and Cordyceps, contain adaptogenic characteristics that aid the body in
adjusting to distressing stimuli [4]. During stressful times, these mushrooms
may aid the body’s stress response and assist in maintaining equilibrium.

Reishi and Cordyceps are both regarded as adaptogens. Adaptogens assist the
body’s stress response and aid in preserving equilibrium in difficult
circumstances. In Reishi, that comes from substances such as triterpenes,
which are thought to modify the body’s stress hormones and may lessen
physiological reactions associated with stress. Finally, Cordyceps increases
physical stamina and endurance, potentially enhancing stress resistance.

While these pathways are still being investigated, taking supplements made
from adaptogenic mushrooms may help promote a more balanced stress response.

4) May Lower Blood Pressure

Research shows that mushrooms like maitake and shiitake could benefit
cardiovascular health [5]. These mushrooms can be consumed or used as
supplements to help decrease blood pressure and improve heart health in
general. Shiitake and maitake mushrooms contain compounds like eritadenine and
beta-glucans that may affect blood pressure regulation.

5) Gut Health

Several mushrooms, including chaga, have been connected to advantages for
intestinal health. Antioxidants found in Chaga mushrooms may help to
maintain a healthy gut microbiome [6]. These antioxidants might encourage
healthy digestion and safeguard gastrointestinal cells. Supplements made from
the Chaga mushroom may inadvertently improve general health by fostering a
healthy gut environment.

Side Effects of Mushroom Supplements

Even though mushroom supplements are considered a safe option that most people
will tolerate, there are some potential side effects to be aware of:

  • Allergic Reactions:You may
    have an allergy to a particular type of mushroom that causes various
    reactions, from a skin rash to difficulty breathing. If you are sensitive
    to mushrooms, see a doctor before taking any mushroom supplements.

  • Digestive Issues:Large doses
    of some mushroom supplements may result in gastrointestinal problems such
    as upset stomach, gas, or bloating.

  • Medication Interactions:Some
    mushroom supplements may interact with prescription medications,
    especially those that affect blood clotting, blood pressure, or immune
    system function. If you use medication, check with your doctor before
    taking mushroom supplements.

  • Specific Health Conditions:People who already have a medical condition, such as a liver
    disorder, immune system disorder, or blood disorder, should exercise
    caution and see a doctor before using mushroom supplements.

best mushroom supplement for brain health

What To Look For When Buying Mushroom Supplements:

When buying high-quality mushroom supplements that will provide the health
support you want, making an informed decision is essential. Here are some
important considerations to bear in mind:

1) Ingredients

Look for a product with an ingredient list that makes it obvious which kind of
mushroom was used and whether it was a combination or a single mushroom.
Ensure the product contains the particular species of mushroom you’re looking

Finally, think about varying your consumption by selecting supplements that
include a variety of mushroom species. Reishi, Lion’s Mane, Cordyceps, Chaga,
Shiitake, and other varieties all have different advantages.

2) Part Of The Mushroom Used

Different portions of mushrooms have varying amounts of bioactive substances.
Verify whether the supplement uses mycelium, the fruiting body, or both.
Fruiting bodies frequently have larger levels of beneficial ingredients and
can, therefore, be considered more pure mushroom supplements.

3) Dosage

Pay close attention to the suggested dosage. Effective dosages can change
depending on the kind of mushroom and the particular benefits you’re looking
for, so make sure the supplement contains an adequate dose.

4) Extraction Method

Mushroom supplements may undergo various extraction procedures to concentrate
bioactive ingredients. Look for supplements that use efficient extraction
techniques like hot water or dual extraction.

5) Form

Pick a form that matches your preferences. Powders can be mixed into foods or
beverages, whereas capsules are more practical for on-the-go use. Tinctures
have a rapid absorption time.

6) Testing/transparency

Choose brands that place a high priority on quality and openness. Look for
supplements that have undergone independent testing for toxins, efficacy, and
purity. Some brands offer Certificates of Analysis (CoA) for quality

7) Reviews

Check out consumer testimonials and feedback from reliable sources. You can
learn about a supplement’s tolerability and effectiveness from these sources.

8) Price

Although quality has a price, stay away from excessively cheap solutions that
can have poor quality. Compare prices across recognized brands to get a gauge
of what a fair price is.

best mushroom supplement for depression

Mushroom Supplements FAQs

Here are the answers to the most frequently asked questions we’re asked about
mushroom supplements:

What mushroom supplement brand is best?

Based on our extensive research, we believe that the best overall mushroom
supplement brand on the current market is Longevity Botanicals. Four of their
mushroom supplements have made it to our top 8 list, including ‘best overall’
– that’s quite a feat. Longevity Botanicals was founded in 2015 and aims to
‘provide high-quality, high-value products created by health experts that
consumers can trust.’ Based on the mushroom products we’ve checked out,
they’re doing a great job fulfilling that mission.

Do mushroom supplements really work?

Whether a mushroom supplement works depends on what you want to get from it,
the type of mushroom included, the dosage, and the way your body reacts to the
supplement. There is evidence that such varieties as Reishi, Lion’s Mane, and
Cordyceps mushrooms can strengthen the immune system, boost brain power, and
reduce stress levels. Still, it is essential to remember that, despite
encouraging research, the effects of mushroom supplements may not be as strong
as the marketing promises.

Which is better, Reishi or Cordyceps?

The choice between Reishi and Cordyceps depends on what you want from your
supplement. Reishi mushrooms are stronger in terms of possessing
immunity-boosting properties thanks to such bioactive compounds as
beta-glucans and triterpenes.

Reishi possesses adaptogenic properties that may help the body adjust to
stress. There is also some evidence that Reishi can help maintain healthy
cholesterol and blood pressure levels.

Cordyceps mushrooms are thought to increase energy production and oxygen use,
possibly resulting in increased physical endurance and stamina. They have also
been researched for their potential to support respiratory function.

Cordyceps is frequently regarded as an adaptogen, just like Reishi, so it can
also help people adjust to stress. Your health objectives will ultimately
determine whether you choose Cordyceps or Reishi. Reishi can be a fantastic
choice if you’re trying to support your immune system and general health.
Cordyceps may be more appropriate if you’re looking to improve your physical
stamina and respiratory health.

Which is the most beneficial mushroom?

Finding the “most beneficial” medicinal mushroom supplements can be complex
because different mushroom species provide a range of potential health
benefits, and what is most beneficial can change based on personal health
objectives and needs. However, three species stand out for their potential
health benefits:

  1. Reishi:Reishi is frequently
    called the “king of mushrooms.” It has been used in conventional medicine
    for its immune-boosting effects, stress adaptation benefits, and potential
    cardiovascular advantages.

  2. Lion’s Mane:This species is
    prized for its potential cognitive benefits. It has elements that could
    promote nerve growth factors, enhancing memory, learning, and general
    cognitive function.

  3. Cordyceps:Cordyceps has long
    been prized for its potential to improve stamina and athletic prowess. It
    is said to enhance energy production and oxygen uptake, making it
    appealing to athletes and anyone looking to gain more endurance.

the best mushroom supplements

Summary Of The Best Mushroom Supplements

From immune support to cognitive enhancement and stress adaptation to heart
health, mushrooms provide a spectrum of health advantages. By harnessing the
power of these fungi in supplement form, you can unlock a path to holistic

The best mushroom supplement for overall wellness is Longevity Botanicals
Power Blend 15, which combines the power of no less than 15 mushroom species,
each of which has been extracted using the superior hot water method.

The best mushroom supplement for brain health is Transparent Labs Shroom
Stack, combining the brain-boosting power of certified organic mushrooms:
Reishi, Lion’s Mane, and Cordyceps. If you’re looking for a supplement to help
combat stress and anxiety, the best mushroom supplement for anxiety is
Longevity Botanicals Super Six Blend, which combines the six best
stress-fighting mushroom species.

best mushroom supplement reddit

The appropriately named Power Blend 15 provides 1600mg of hot-water extracted mushrooms. Made from a blend of the most well-known and effective mushrooms, Power Blend 15 is a great way to…

For more powerful mushroom products, try our Best Lion’s Mane Supplements, Best Chaga Supplements For Immune System Support, and our Best Cordyceps Supplements.


  1. Rop O, Mlcek J, Jurikova T. Beta-glucans in higher fungi and their
    health effects. Nutr Rev. 2009 Nov;67(11):624-31. doi:
    10.1111/j.1753-4887.2009.00230.x. PMID: 19906249.

  2. Xu, J., Xu, D., Hu, Q., Ma, N., Pei, F., Su, A., & Ma, G. (2023).
    Immune regulatory functions of biologically active proteins from edible
    fungi. Frontiers in Immunology, 13.

  3. Lai PL, Naidu M, Sabaratnam V, Wong KH, David RP, Kuppusamy UR,
    Abdullah N, Malek SN. Neurotrophic properties of the Lion’s mane
    medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from
    Malaysia. Int J Med Mushrooms. 2013;15(6):539-54. doi:
    10.1615/intjmedmushr.v15.i6.30. PMID: 24266378.

  4. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes)
    and maitake (Grifola frondosa) mushrooms on blood pressure and plasma
    lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo).
    1987 Oct;33(5):341-6. doi: 10.3177/jnsv.33.341. PMID: 3443885.

  5. Antioxidants and cancer prevention. National Cancer Institute. (n.d.).

#Mushroom #Supplements #Boost #Health

Leave a Comment