Rare HIV-to-HIV transplant across different blood groups | India News – Times of India

MUMBAI: When a 48-year-old cotton trader from Aurangabad needed a kidney transplant, his 45-year-old wife did what many in similar circumstances do: offer one of her kidneys.
But two factors made this transplant different from other kidney transplants: both were HIV-positive and their blood groups didn’t match. The wife had B blood type, while the husband’s blood group was A. “We did a complete search of medical literature before concluding that this is perhaps the first HIV-to-HIV and ABO incompatible (when the donor’s and recipients’ blood types are not compatible) transplant,” said nephrologist Dr Sachin Soni from Medicover Hospital, Aurangabad. The transplant was carried out on January 18.
There have been a handful of instances in the world, including India, of HIV-to-HIV transplants. “But the challenge was to prepare an HIV-positive recipient to receive a kidney from a donor with a different blood group,” said Dr Soni. In ABO incompatible transplants, the recipients have to be preconditioned with immunosuppressants and a type of blood plasma treatment before the operation to prevent the body from rejecting the foreign organ.
“Thankfully, both my parents are doing well,” said his son. The family got Rs 2 lakh from the CM’s Relief Fund, and raised the remaining Rs 4 lakh from family and friends.
In 2010, an HIV-positive person underwent a kidney transplant for the first time in Mumbai after his mother donated an organ. Jaslok Hospital’s Dr Madan Bahadur, who was treating that patient, said in the Aurangabad HIV-to-HIV transplant “the risk is the donor’s health in the future.”

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